Hello to Everyone at Aging fabulous

Hi everyone! My name is Beth Bender and I am the new blogger for Aging fabulous. I want to introduce myself to everyone out there who loves Aging Fabulous as much as I do and to say how happy I am to be a part of the b5 family. I am excited to share with you the latest in beauty products, and trends, as well as things I have learned as a make-up artist over the last fifteen years. I am always available to answer questions or give beauty advice to anyone who needs it and encourage those who do to email me personally.

As Teri mentioned I am also the face behind beth bender beauty and inventor of the Get in Line Eyeliner & Stencil kit. I am just as much a make-up junkie as the next gal and love, love, love, beauty products!  Working on set and behind the scenes of editorial pages for some of the industry’s biggest beauty magazines has given me access to the latest beauty finds, tips and trends.

A native New Yorker now living in Los Angeles, whether I am working or not I am always connecting with Hollywood’s top experts for make-up, hair and skin care, and getting the buzz on celebrity beauty must haves.  As a woman in her 40’s I celebrate beauty everyday and look forward to bringing you lots of new and exciting ways for Aging Fabulous.

Here’s to celebrating beauty at any age!

xo,

Beth

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Good-Bye my Aging Fabulous Friends…

I am sad to say that I will no longer be writing Aging Fabulous here for b5media. I have been honored to get to know so many of you here through my posts and your comments over the last 20 months. I have loved every minute of it.

My life is so busy right now that I have decided to concentrate and grow what is my own. I will continue to be online through my original blog Beautiful Makeup Search and another that I started earlier this year called Aging Beautiful. So to keep up with the latest and greatest from me in makeup and anti-aging beauty and beyond, please keep me in your list of favorites and bookmarks with those blogs.

It has been an honor to get to know so many of you and I hope you have enjoyed my writings as well. Stay tuned for more great aging fab news here on Aging Fabulous with Beth Bender who will be taking over for me. Beth is no stranger to beauty as she has her own line of beauty products, and I am sure you will come to enjoy getting to know her here now at Aging Fabulous.

I want to thank you all for reading Aging Fabulous on a daily basis and I extend my best wishes to all of you, and to Beth, along the rest of my friends in the Beauty & Style Channel at b5.

Don’t be strangers!!!

xo, Teri

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Melatonin and Hidden Complexity

A couple of papers to compare and contrast:

Melatonin in relation to the "strong" and "weak" versions of the free radical theory of aging:

While the data supporting a role for melatonin in forestalling aging and prolonging life span per se is not compelling, the findings related to melatonin's ability to reduce the severity of a variety of age-related diseases that have as their basis free radical damage is convincing.

Melatonin prevents age-related mitochondrial dysfunction in rat brain via cardiolipin protection

Melatonin has been shown to possess antioxidant properties and to reduce oxidant events in brain aging. .... We found [that a number of] mitochondrial parameters were significantly altered with aging, and that melatonin treatment completely prevented these age-related alterations. These effects appear to be due, at least in part, to melatonin's ability to preserve the content and structural integrity of cardiolipin molecules, which play a pivotal role in mitochondrial bioenergetics.

Which is interesting to say the least; I would have lumped melatonin in with all the other antioxidant supplements - just because a chemical happens to affect some aspects of your biochemistry doesn't mean that ingesting it is going to have any positive benefit.

I have to wonder at what complexity is hidden here: a mechanism completely prevents alterations in mitochondrial parameters, and yet doesn't do anything for life span? Compare that with antioxidant chemicals targeted directly to mitochondria, which lead to significant extensions of healthy life. Mitochondria are complex objects, and (a) the state of their membranes, (b) the working of their inner processing mechanisms, and (c) the effects they have on their cell are not linked in straightforward ways.

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Dr. Robert Rey Sensual Solutions.

Don’t be confused. Sensual Solutions from the one and only Dr. 90210 Robert Rey is an anti-aging system of skin care and body care products. The title sort of makes me chuckle.

dr_robert_ray_skincare

The only skincare approach to ageless, timeless beauty for women who want doctor’s office results with no appointment necessary.

I don’t know. It seems that to me that Dr. Rey probably was contacted by a private label line to put his name on. I seriously cannot see him in the lab creating skin care and beauty products. I wonder.

Take a look at the entire Sensual Solutions line up.

Would you try these Sensual Solutions products (sold exclusively at Nordstrom) from Dr. Rey? And if you have used them, do dish in the comments.

image credit: Nordstrom

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On Risk and Acting Appropriately

The rational actor looks at risks to life and health ahead and acts to minimize those risks. Since we all have limited time and resources, we have to prioritize: we make lists, in our heads if nowhere else, putting the most likely and terrible outcomes up at the top. Highly unlikely but terrible outcomes don't receive much attention: meteors, lightning strikes, that sort of thing. Likely but merely unpleasant events might just be suffered as a cost of getting on with life: catching the flu is an obnoxious happenstance, but not particularly threatening for most of us. There are more important things to worry about while buying insurance and otherwise taking care of essentials.

So you end up with a list involving fires, car accidents, sudden implosion of the company you work for, that sort of thing. In that, most of us are not being terribly rational, as aging isn't on the list. It is absolutely going to happen, and it leads to the most terrible personal consequence possible - death - via numerous other very nasty personal consequences. Alzheimer's, heart disease, cancer, and all the rest. We all have a 100% chance of aging as things stand, and it's the worst thing that will happen to most of us. So why isn't it up near the top of that priority list?

On that subject, thoughts from a bioethicist I seem to be linking to a lot of late. Replace "we" with "I" and "society" with "an individual" and it works just fine:

the following four issues are vital:

1. The certainty of the harm (e.g. 0.1% vs 70% chance)
2. The severity of the harm (e.g. broken leg vs death)
3. The likelihood of mitigating the harm (e.g. 0.1% vs 70%)
4. The cost of mitigating the harm ($1 billion vs $1 trillion)

...

Aging increases one’s risk of disease and death. So the empirical evidence clearly shows that aging scores very high on (1) and (2). These facts alone show that aging is a BIG problem.

How about issues (3) and (4)? People are most likely to (mistakenly) assume aging research scores low on both these fronts. That is, people are skeptical that we can actually modify the biological processes of aging. But there are countless experiments in a variety of organisms that show aging is not immutable. And so the goal of retarding human aging scores reasonably well on (3). And once you add considerations (1) and (2) into the mix, it becomes evident that the current neglect of aging research is unjustified.

People will also falsely assume that (4) will require vast amounts of money. But here one must put things in their proper context. A lot of money compared to what? What we spend on national defence? National defense spending in the U.S. has reached approximately $1,600 per capita, compared to $97 per capita for federal spending on biomedical research (source)

Which I think is a fair summary of where things stand - aging is terrible, but those who would act to materially support longevity science don't believe that progress is possible, or that progress is cost-effective. Meanwhile, individuals pledge significant time and money for food, entertainment, and geopolitical machinations. You might want to refresh your memory as to the Strategies for Engineered Negligible Senescence (SENS) cost breakdown: a billion dollars over ten years to develop the medical technologies capable of rejuvenating aged mice in the laboratory, each of the seven branches of SENS requiring something like $15 million per year over that time.

Effective research is cheap compared to almost everything else connected with aging: the loss of wealth, deteriorating health, loss of contributing members of society, the elderly care infrastructure, and more. It's a great pity that support and fundraising lags so far behind the potential of longevity science.

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